Comments on: Cadherins, Part 1 http://telicthoughts.com/cadherins-part-1/ An independent blog about intelligent design Thu, 08 Jan 2009 17:16:17 +0000 http://wordpress.org/?v=2.6.3 By: janeashley22 http://telicthoughts.com/cadherins-part-1/#comment-208599 janeashley22 Mon, 24 Nov 2008 06:21:10 +0000 http://telicthoughts.com/cadherins-part-1/#comment-208599 E-cadherin is probably the best understood cadherin. It consists of 5 cadherin repeats (EC1 ~ EC5) in the extracellular domain, one transmembrane domain, and an intracellular domain that binds p120-catenin and beta-catenin. The intracellular domain contains a highly-phosphorylated region vital to beta-catenin binding and therefore to E-cadherin function. Beta-catenin can also bind to alpha-catenin. Alpha-catenin participates in regulation of actin-containing cytoskeletal filaments. In epithelial cells, E-cadherin-containing cell-to-cell junctions are often adjacent to actin-containing filaments of the cytoskeleton. ------------------------------ janeashley <a href="http://www.widecircles.com" rel="nofollow">Social Bookmarking</a> E-cadherin is probably the best understood cadherin. It consists of 5 cadherin repeats (EC1 ~ EC5) in the extracellular domain, one transmembrane domain, and an intracellular domain that binds p120-catenin and beta-catenin. The intracellular domain contains a highly-phosphorylated region vital to beta-catenin binding and therefore to E-cadherin function. Beta-catenin can also bind to alpha-catenin. Alpha-catenin participates in regulation of actin-containing cytoskeletal filaments. In epithelial cells, E-cadherin-containing cell-to-cell junctions are often adjacent to actin-containing filaments of the cytoskeleton.
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janeashley
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]]> By: Mike Godfrey http://telicthoughts.com/cadherins-part-1/#comment-109331 Mike Godfrey Tue, 29 May 2007 16:07:49 +0000 http://telicthoughts.com/cadherins-part-1/#comment-109331 Hi Mike , thanks for this series -not too sure it will rate with 'Friends' but it is interesting-awaitng the next installment. cheers Mike Hi Mike ,
thanks for this series -not too sure it will rate with 'Friends' but it is interesting-awaitng the next installment.
cheers
Mike

]]> By: MikeGene http://telicthoughts.com/cadherins-part-1/#comment-109163 MikeGene Tue, 29 May 2007 03:01:57 +0000 http://telicthoughts.com/cadherins-part-1/#comment-109163 Hi TP, Yes, I'll try to post Part 2 tomorrow. Hi TP,

Yes, I'll try to post Part 2 tomorrow.

]]> By: Thought Provoker http://telicthoughts.com/cadherins-part-1/#comment-109149 Thought Provoker Tue, 29 May 2007 02:09:31 +0000 http://telicthoughts.com/cadherins-part-1/#comment-109149 Hi Mike, You wrote... <blockquote>But it gets better"¦..</blockquote> Does that mean part 2 is on its way? Either way, thanks for the video clips. Regards, TP Hi Mike,

You wrote…

But it gets better"¦..

Does that mean part 2 is on its way?

Either way, thanks for the video clips.

Regards,
TP

]]> By: Mung http://telicthoughts.com/cadherins-part-1/#comment-109143 Mung Tue, 29 May 2007 01:53:21 +0000 http://telicthoughts.com/cadherins-part-1/#comment-109143 I'm looking for my calcium pills. I wouldn't want my body to fall apart :shock: I'm looking for my calcium pills. I wouldn't want my body to fall apart :shock:

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