Proteins - Telic Thoughts

Archive for the 'Proteins' Category

Playing with Progress

Posted in Proteins on July 24th, 2008 by Bradford

Is a birthday coming up? Anniversary? Do you like computer games? Biology? If you answered yes to the last two consider Foldit. Consider this- How does my game playing contribute to curing diseases? From the site:

We’re collecting data to find out if humans' pattern-recognition and puzzle-solving abilities make them more efficient than existing computer programs at pattern-folding tasks. If this turns out to be true, we can then teach human strategies to computers and fold proteins faster than ever!

This may be a more entertaining approach to protein folding than the prior blog on Stylus.

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Better Models

Posted in Evolution, Proteins on July 22nd, 2008 by Bradford

In their PLOS One paper titled Stylus: A System for Evolutionary Experimentation Based on a Protein/Proteome Model with Non-Arbitrary Functional Constraints, Douglas D. Axe, Brendan W. Dixon and Philip Lu of the Biologic Institute, introduced new software known as Stylus. Stylus is intended to more realistically model proteins and evolutionary constraints with more accurate linkage of protein structure to function. The nature of some current models, compromises accurate assessments of protein transition possibilities and the mapping of sequences to changes in function.

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