Cadherins, Part 1
by MikeGeneHere is a little background information about the formation of a multi-cellular state:
Okay, now we are ready to meet an important player, the cadherins. Notice how the eukaryotic cell design seems awfully well-suited to facilitate multi-cellular existence, where a network of cytoskeletons are physically linked together to become one:
But it gets better"¦..



















May 28th, 2007 at 9:53 pm
I'm looking for my calcium pills. I wouldn't want my body to fall apart
Comment by Mung — May 28, 2007 @ 9:53 pm
May 28th, 2007 at 10:09 pm
Hi Mike,
You wrote…
Does that mean part 2 is on its way?
Either way, thanks for the video clips.
Regards,
TP
Comment by Thought Provoker — May 28, 2007 @ 10:09 pm
May 28th, 2007 at 11:01 pm
Hi TP,
Yes, I'll try to post Part 2 tomorrow.
Comment by MikeGene — May 28, 2007 @ 11:01 pm
May 29th, 2007 at 12:07 pm
Hi Mike ,
thanks for this series -not too sure it will rate with 'Friends' but it is interesting-awaitng the next installment.
cheers
Mike
Comment by Mike Godfrey — May 29, 2007 @ 12:07 pm
November 24th, 2008 at 2:21 am
E-cadherin is probably the best understood cadherin. It consists of 5 cadherin repeats (EC1 ~ EC5) in the extracellular domain, one transmembrane domain, and an intracellular domain that binds p120-catenin and beta-catenin. The intracellular domain contains a highly-phosphorylated region vital to beta-catenin binding and therefore to E-cadherin function. Beta-catenin can also bind to alpha-catenin. Alpha-catenin participates in regulation of actin-containing cytoskeletal filaments. In epithelial cells, E-cadherin-containing cell-to-cell junctions are often adjacent to actin-containing filaments of the cytoskeleton.
——————————
janeashley
Social Bookmarking
Comment by janeashley22 — November 24, 2008 @ 2:21 am