Here is a little background information about the formation of a multi-cellular state:
Okay, now we are ready to meet an important player, the cadherins. Notice how the eukaryotic cell design seems awfully well-suited to facilitate multi-cellular existence, where a network of cytoskeletons are physically linked together to become one:
But it gets better"¦..
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| The Design Matrix: A Consilience of Clues by Mike Gene |
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| Your Inner Fish: A Journey into the 3.5-Billion-Year History of the Human Body |
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| Catalyzing Inquiry at the Interface of Computing and Biology |
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| System Modeling in Cellular Biology: From Concepts to Nuts and Bolts |
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| The Plausibility of Life By Marc W. Kirschner and John C. Gerhart |
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| Agents Under Fire by Angus Menuge |
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| Life's Solution by Simon Conway Morris |
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| Information Theory, Evolution and the Origin of Life by Hubert P. Yockey |
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| The Fifth Miracle by Paul Davies |
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| Nature, Design, and Science by Del Ratzsch |
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| Origination of Organismal Form by Muller & Newman |
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| Biased Embryos and Evolution by Wallace Arthur |
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| Rare Earth by Peter Ward and Donald Brownlee |
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| The Privileged Planet by Guillermo Gonzalez and Jay Richards |
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| The Way of the Cell by Franklin Harold |
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| The Volitional Brain by Benjamin Libet |
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| Evolution in Four Dimensions by Eva Jablonka & Marion Lamb |
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| The Evolution-Creation Struggle by Michael Ruse |
May 28th, 2007 at 9:53 pm
I'm looking for my calcium pills. I wouldn't want my body to fall apart
Comment by Mung — May 28, 2007 @ 9:53 pm
May 28th, 2007 at 10:09 pm
Hi Mike,
You wrote…
Does that mean part 2 is on its way?
Either way, thanks for the video clips.
Regards,
TP
Comment by Thought Provoker — May 28, 2007 @ 10:09 pm
May 28th, 2007 at 11:01 pm
Hi TP,
Yes, I'll try to post Part 2 tomorrow.
Comment by MikeGene — May 28, 2007 @ 11:01 pm
May 29th, 2007 at 12:07 pm
Hi Mike ,
thanks for this series -not too sure it will rate with 'Friends' but it is interesting-awaitng the next installment.
cheers
Mike
Comment by Mike Godfrey — May 29, 2007 @ 12:07 pm
November 24th, 2008 at 2:21 am
E-cadherin is probably the best understood cadherin. It consists of 5 cadherin repeats (EC1 ~ EC5) in the extracellular domain, one transmembrane domain, and an intracellular domain that binds p120-catenin and beta-catenin. The intracellular domain contains a highly-phosphorylated region vital to beta-catenin binding and therefore to E-cadherin function. Beta-catenin can also bind to alpha-catenin. Alpha-catenin participates in regulation of actin-containing cytoskeletal filaments. In epithelial cells, E-cadherin-containing cell-to-cell junctions are often adjacent to actin-containing filaments of the cytoskeleton.
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janeashley
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Comment by janeashley22 — November 24, 2008 @ 2:21 am